| abstract |
Provided are BARD1 isoforms and uses thereof in lung cancer and colorectal cancer. A recombinant siRNA molecule that binds to a single-stranded or double-stranded RNA molecule, wherein the single-stranded or double-stranded RNA molecule comprises a specific amino acid sequence, BARD1 (breast cancer predisposition gene BRCA1-associated RING) Domain protein 1) for treating and / or preventing lung cancer and colorectal cancer, characterized in that it comprises mRNA encoding at least one of the isoforms and thereby inhibits the expression of said BARD1 isoform Said siRNA molecule for use in a method. [Selection figure] None |