| abstract |
Disclosed is a therapeutic compound which is an inhibitor of monoamine oxidase (MAO) enzyme function. A compound represented by formula IIa and a salt thereof. (R 1 is C 1-6 alkyl substituted with halogen, cyano or nitro; A 1 is N or CR 2 ; R 2 is C 1-6 alkyl; A 2 and A 3 are each independently O or N; Z 1 Is S; Z 2 and Z 3 are each independently CR 5 ; R 5 is H or C 1-6 alkyl; X is C═O; Y is optionally substituted piperidinyl; the dotted line is any double bond ) [Selection figure] None |