| abstract |
The present invention is a composition comprising a lipid composition, wherein the lipid composition is of the formula (I) wherein n is any one of 1, 2, 3, and 4, wherein m is any one of 1, 2, and 3, and Y ′ is an anion, wherein R 1 and R 2 are individually and independently linear C12-C18 alkyl. And a sterol compound selected from the group consisting of cholesterol and stigmasterol, wherein the sterol compound is selected from the group consisting of linear C12 to C18 alkenyl] A PEGylated lipid, wherein the PEGylated lipid comprises a PEG moiety, wherein the PEGylated lipid is of formula (II) wherein R3 and R4 are each individually and independently Chain C13-C17 Alky And p is any integer from 15 to 130], PEGylated phosphoethanolamine of formula (III), wherein R5 is a linear C7-C15 alkyl and q is PEGylated ceramide represented by the formula (IV), wherein R6 and R7 are each independently and independently a linear C11-C17 alkyl, Wherein r is any integer from 15 to 130], and a PEGylated lipid selected from the group consisting of PEGylated diacylglycerol. |