abstract |
As used herein, methods, compositions, and kits for treating myeloproliferative disorders or neoplasms, including polycythemia vera, primary myelofibrosis, thrombocythemia, and essential thrombocythemia, Provided. As used herein, an effective amount of one, two, or more therapeutic agents is used including a phosphatidylinositol 3-kinase delta (PI3Kδ) inhibitor, a Janus kinase (JAK) inhibitor, or a combination thereof. This provides methods, compositions, articles of manufacture, and kits for treating hyperproliferative disorders. |