http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016537027-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-311 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2016537027-A |
titleOfInvention | Polynucleotide construct having a disulfide group |
abstract | The present invention provides a polynucleotide construct comprising one or more components (i) having a disulfide bond, wherein each of the one or more components is bound to an internucleotide bridging group or terminal group of the polynucleotide construct. And each of the one or more components (i) is characterized by a polynucleotide construct containing one or more bulky groups proximal to the disulfide group. The invention also provides a polynucleotide construct comprising one or more components (i) having disulfide bonds, wherein each of the one or more components (i) is an internucleotide bridging group or terminal of the polynucleotide construct. Each of one or more components (i) contains at least 4 atoms in the chain between the disulfide bond and the internucleotide bridging group or the terminal phosphorus atom; Here, the chain features a polynucleotide construct that does not contain phosphates, amides, esters, or alkenylene. The invention further features a method of delivering a polynucleotide to a cell using the polynucleotide construct of the invention. [Selection figure] None |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020512843-A |
priorityDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1731.