http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016535271-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-06113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2016535271-A |
| titleOfInvention | Genetically encoded probes for the determination of pyruvate concentration and methods of use thereof. |
| abstract | The present invention relates to a novel optical tool for detecting and quantifying pyruvate in samples, tissues, and cellular and intracellular compartments with high spatiotemporal resolution. This is a pyruvate sensor based on Forster Resonance Energy Transfer (FRET), which contains a bacterial PdhR transcription factor between any suitable donor fluorescent protein portion and acceptor fluorescent protein portion. It is out. The present invention also provides for the quantification of pyruvate transporter activity, for the determination of cellular pyruvate production rate and pyruvate consumption rate, and for the direct determination of mitochondrial pyruvate consumption rate in intact cells. For the use of this new optical tool. |
| priorityDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1602.