abstract |
The present invention relates to general formula (I) [Chemical 1] (I) In which the groups R 1 , R 2 , X, Y and Z are as defined in claim 1. Which have valuable pharmacological properties, in particular bind to AMP-activated protein kinase (AMPK) and modulate its activity. These compounds are suitable for the treatment and prevention of diseases that can be affected by this receptor, for example metabolic diseases, in particular type 2 diabetes. |