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filingDate 2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2016534810-A
titleOfInvention Leak-free stopper for syringe assemblies with low opening force and durability
abstract A thermoplastic elastomer stopper that satisfies the desired material properties of the stopper for the syringe assembly is disclosed. The compression set when the thermoplastic elastomer stopper of the present disclosure is held at 70 ° C. for 22 hours at 25% compression is 50% or less. The hardness of the thermoplastic elastomer stopper of the present disclosure is 40 to 70 Shore A. The viscosity of the thermoplastic elastomer stopper of the present disclosure is measured at 205 ° C. using a capillary rheometer (die: round hole length 20 mm / diameter 1 mm / 180 degree inlet, piston: d = 15 mm, and melt time = 7 minutes). At a shear rate of 1,000 seconds -1 at 70.0 Pa · s or higher, at a shear rate of 10,000 seconds -1 at 12.0 Pa · s or higher, and at a shear rate of 50,000 seconds -1 at 3.0 Pa · s. s or more. The non-lubricated stopper exhibits the required functional performance of the lubricated stopper.
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