| abstract |
Polymer-flavonoid conjugates are provided. In accordance with the present invention, flavonoid grafted and flavonoid terminated polymer conjugates are disclosed. The coupling of flavonoids to the polymer has been achieved via thiol bonds. The method of the present invention makes it possible to make a zygote in high yield by avoiding complicated purification steps. Conjugates can be readily autoxidized to hydrogels and have benefits in many biomedical applications where higher flavonoid stability is required. Hydrogels could potentially be used as intra-articular replacements, anti-adhesion films or skin fillers. |