http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016533709-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
| filingDate | 2014-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2016533709-A |
| titleOfInvention | Synthetic combinatorial AAV capsid library for targeted gene therapy |
| abstract | The various strategies for generating capsid libraries that have been developed so far all suffer from sequence bias or limited diversity. [Solution] One for the production of modified adeno-associated virus (AAV) cap genes and the production of chimeric AAV vectors and combinatorial libraries of virions, for the selection of virions that present cell-specific affinity, and in particular embodiments one Alternatively, compositions and methods for the production of helper vectors containing multiple modified AAV cap genes are disclosed. The synthetic combinatorial AAV capsid libraries of the present invention are useful for the introduction of one or more nucleic acid molecules into selected target host cells. The viral vectors and gene constructs disclosed herein are also useful for various gene therapy diagnostics and / or treatment regimens. [Selection] Figure 2 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020508667-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7237843-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767346-B2 |
| priorityDate | 2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1520.