http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016531881-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4166 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
filingDate | 2014-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2016531881-A |
titleOfInvention | Enzalutamide in combination with afreseltiv to treat cancer |
abstract | Androgen receptor inhibitors such as 4- (3- (4-cyano-3- (trifluoromethyl) phenyl) -5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)- 2-Fluoro-N-methylbenzamide or a pharmaceutically acceptable salt thereof and an AKT inhibitor compound such as N-{(1S) -2-amino-1-[(3-fluorophenyl) methyl] ethyl}- Novel comprising 5-chloro-4- (4-chloro-1-methyl-1H-pyrazol-5-yl) -2-thiophenecarboxamide or a pharmaceutically acceptable salt thereof, and any additional antineoplastic agents A pharmaceutical composition comprising the combination and the combination and composition for the treatment of conditions where androgen receptor inhibition and / or AKT inhibition is beneficial, eg, cancer. How to. |
priorityDate | 2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 538.