| abstract |
The present invention provides compounds, compositions thereof, and methods of using them. The compounds of the invention and pharmaceutically acceptable compositions thereof are useful for treating various diseases, disorders or conditions associated with modulation of signaling pathways involving IRAK kinase. Such diseases, disorders, or conditions include those described herein. The compounds provided by the present invention also provide for the study of IRAK enzymes in biological and pathological phenomena; the study of intracellular signaling pathways that occur in body tissues; and new IRAK inhibitors or kinases, signaling pathways, and Useful for comparative evaluation in vitro or in vivo of other regulators of cytokine levels. |