Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2875 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2014-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2016528504-A |
titleOfInvention |
Biomarkers for prostate cancer |
abstract |
The present disclosure provides methods of using biomarkers to improve prostate morphology diagnosis. The method comprises examining a biological sample obtained from an individual for interleukin-8 (IL-8), tumor necrosis factor α (TNF-α) and soluble tumor necrosis factor-α receptor 1 (sTNFR1). In addition, a test for prostate serum antigen (PSA) may be included. The combined use of these markers provides a test that is more sensitive and specific than PSA to distinguish benign versus malignant prostate disease and / or localized CaP versus metastatic CaP, and PSA-based CaP diagnosis It shows that the specificity and sensitivity of can be significantly enhanced by measuring IL-8, TNF-α and sTNFR1. [Selection figure] None |
priorityDate |
2013-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |