abstract |
Amorphous N-[(3aR, 4R, 4aR, 5aS, 6S, 6aS) -3 for the treatment or prevention of viral infections and associated diseases, particularly those viral infections and related diseases caused by orthopoxvirus , 3a, 4,4a, 5,5a, 6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop [f] isoindol-2 (1H) -yl] -4- (trifluoromethyl ) -Methods for the preparation of benzamides are disclosed. N-[(3aR, 4R, 4aR, 5aS, 6S, 6aS) -3,3a, 4,4a, 5,5a, 6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop [f A process for the preparation of an amorphous solid dispersion of isoindole-2 (1H) -yl] -4- (trifluoromethyl) -benzamide is also disclosed. |