| abstract |
Compound 1- (5-chloro-6-methyl-1- (6- (trifluoromethyl) pyridin-2-yl) -1H-benzo [d] imidazol-2-yl) -N-((3S, 4R) -4-hydroxytetrahydrofuran-3-yl) piperidine-4-carboxamide and 1- (6-chloro-5-methyl-1- (6- (trifluoromethyl) pyridin-2-yl) -1H-benzo [d] Imidazol-2-yl) -N-((3S, 4R) -4-hydroxytetrahydrofuran-3-yl) piperidine-4-carboxamide, and pharmaceutically acceptable salts thereof, and any one of these compounds A pharmaceutical composition comprising. The compound is an inflammatory disease; autoimmune disease; pain; respiratory disorder; cancer; cardiovascular disease; neurodegenerative disease; bone disease; disorder due to familial adenomatous polyposis (FAP) disease; overactive bladder; Useful for the treatment and / or prevention of disorders selected from associated anorexia. [Selection figure] None |