| abstract |
Disclosed in the present invention is a substance having tyrosine kinase inhibitory activity and a preparation method and use thereof, which is a compound having the structure of general formula (I), or a geometric isomer and a pharmaceutical salt thereof It is. The present invention establishes through evaluation of tyrosine kinase inhibitory activity and related experiments that these compounds have good tyrosine kinase inhibitory activity and can inhibit various tumor cells. The present invention develops into drugs that prevent and treat tumor diseases, particularly resistant liver cancer, lung cancer and neuroblastoma. [Chemical 1] |