http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016520324-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00 |
filingDate | 2014-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2016520324-A |
titleOfInvention | Control of metabolic flux in cell-free biosynthetic systems |
abstract | In order to produce the desired product of the pathway of interest, a method is provided for controlling metabolic flux rates in a cell-free system containing a series of complex enzymes. In the method of the present invention, metabolic performance parameter measurements are taken by continuous monitoring or intermittent monitoring. Based on metabolic performance parameters, the system (i) alters enzyme levels in the cell-free system; (ii) alters the rate of supply of the substrate controlling the redox flux or carbon flux to the cell-free system; (iii) no Changing the addition of O 2 to the cell line; (iv) controlling the efficiency of the electron transport system by changing the leakage across the membrane, wherein Enzymes present in the pathway that catalyze the desired product. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020137460-A |
priorityDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 839.