| abstract |
Compositions of small molecules, matrices and isolated cells have been described, including methods of preparation and methods for differentiation, transdifferentiation, and growth of animal cells into the osteoblast lineage. Examples of osteogenic materials administered to cells or co-cultured with cells are represented by compounds of formulas II, IV, and VI, independently or preferably in combination with a matrix that provides bone cells. Is done. Small molecule stimulating cells were also combined with a matrix, placed with cell adhesives or material carriers, and placed at sites in animals for bone repair. Cells were also transferred to matrices used for therapeutic purposes using matrices pretreated with compounds of formula II, IV, and VI. |