| abstract |
The present invention is a compound of the following formula or a pharmaceutically acceptable salt thereof. The above compounds are useful as HDAC inhibitors. Wherein each R ′ is independently selected from H and QR 1 , each Q is independently selected from a bond, CO, CO 2 , NH, S, SO, SO 2 or O, and each R 1 is independently H , C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, aryl, heteroaryl, C 1 -C 10 cycloalkyl, halogen, C 1 -C 10 alkylaryl, C 1 -C 10 is selected from alkyl heteroaryl or C 1 -C 10 heterocycloalkyl, each L is selected from nitrogen-containing heteroaryl independently 5-10 membered, W is a zinc-binding group, each R 2 is independently hydrogen or C 1 -C 6 alkyl and R 3 is aryl or heteroaryl. |