| abstract |
The present invention is directed to antibodies having a binding specificity for HGF and fragments thereof. Another embodiment of the invention relates to the antibodies and binding fragments thereof described herein comprising the VH, VL, and CDR polypeptide sequences described herein, and the polynucleotides encoding them. The present invention also contemplates complexes of anti-HGF antibodies and binding fragments thereof that are conjugated to one or more functional or detectable moieties. The present invention also contemplates methods for producing the anti-HGF antibody and binding fragments thereof. Embodiments of the invention also relate to the use of anti-HGF antibodies and binding fragments thereof for the diagnosis, evaluation, and treatment of diseases and disorders associated with HGF. [Selection] Figure 1 |