| abstract |
The present invention optionally provides apoptosis in tumor cells by administering to a patient an effective amount of an N-acyl homoserine lactone analog (AHL), together with a tumor modulating agent such as tumor necrosis factor (TNF) -related apoptosis-inducing ligand (TRAIL). Relates to methods of inducing cell cycle arrest, inhibiting cell proliferation, or any combination thereof. Further provided are novel bioactive analogs of N-acyl homoserine lactones. |