| abstract |
A method is provided for evaluating or treating a patient, eg, a patient having a disorder described herein, the method comprising: a) obtaining a patient sample as needed; b) a reference and Obtaining an evaluation of the sample and / or evaluating the sample for changes in the level of 24 (S) -hydroxycholesterol when compared. This method comprises effective amounts of 24 (S) -hydroxycholesterol or structurally related sterols or steroids, oxysterols, agonists of NMDAR or NMDAR positive allosteric modulators (PAM) or compounds of formula (I) The method may further comprise administering to the patient a compound described herein (eg, responsive to the assessment of the sample). |