| abstract |
Provided herein are compositions, methods, and kits for induction of hematopoietic stem cells or for reprogramming cells to the multipotent state of hematopoietic stem cells. In some embodiments, the composition comprises at least one HSC inducer. Such compositions, methods and kits can be used to induce hematopoietic stem cells in vitro, ex vivo or in vivo as described herein, and regenerate these induced hematopoietic stem cells. Can be used for medical applications and therapy. |