| abstract |
Stable indole-3-propionate of S-adenosyl-L-methionine or a pharmaceutically acceptable salt thereof, and pharmaceutical composition comprising indole-3-propionate, use of indole-3-propionate A method and process for making it are disclosed. An IPA salt of SAMe or a pharmaceutically acceptable salt thereof also increases the level of DNA and RNA methylation in mammals, preferably humans, and the level of SAMe in blood and other tissues or fluids. It is also useful in treating or preventing a wide variety of conditions associated with DNA hypomethylation, RNA hypomethylation, protein hypomethylation, low SAMe blood and tissue levels. |