abstract |
The present application discloses a pharmaceutical composition comprising a class of CETP inhibitors with improved oral bioavailability. The application further discloses compositions comprising a class of CETP inhibitors and at least one solubility improving material and optionally one or more wetting agents. In one aspect, the application provides: a) a CETP inhibitor having the formula (I) or (Ia ′) or (II) or (III), b) at least one solubility-improving material, c) optionally 1 It relates to a pharmaceutical composition comprising seeds or humectants and d) at least one pharmaceutically acceptable additive. |