abstract |
The present invention provides formulas useful as sodium channel blockers: Or pharmaceutically acceptable salts thereof, and compositions containing them, processes for preparing them, methods of their therapeutic use in promoting the application of moisture to mucosal surfaces, and cystic fibrosis It relates to the treatment of diseases including chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema and pneumonia. |