| abstract |
The present invention relates to compounds of formula 1, 2 or 3 wherein A is N or —CR 0 —, wherein R 0 is hydrogen, C 1 -C 6 straight or branched alkyl Z is —CR e —— or —N——, where R e is hydrogen, C 1 -C 6 straight chain or branched alkyl, etc., and R 1 is hydrogen , C 1 -C 6 straight or branched alkyl, etc., R 2 is independently hydrogen, or C 1 -C 6 straight or branched alkyl, R 3 and R 4 are independently And hydrogen, C 1 -C 6 straight chain or branched alkyl, etc., and R 5 and R 6 are independently hydrogen, or C 1 -C 6 straight chain or branched chain alkyl, etc. 8 is hydrogen, C 1 -C 6 straight or branched chain alkyl such as, R 9 and R 10 are independently hydrogen, or , Is C 1 -C 6 straight or branched chain alkyl such as, Q is - CO -, - (CH 2 ) q -, - (CHR s) q - or - (CR s R t) q - it is and wherein, R s and R t are independently C 1 -C 6 straight or branched chain alkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl, Wherein q is 0, 1, 2 or 3 and n is 0, 2, 3, 4 or 5], or a pharmaceutically acceptable salt thereof, a composition containing such a compound And the use of such compounds in the treatment of various diseases, particularly those affected or mediated by androgen receptors. [Chemical 1] |