abstract |
The present invention relates to a method for the diagnosis or prognosis of metastasis in prostate cancer comprising determining whether the c-MAF gene is amplified in a primary tumor sample. Similarly, the present invention also provides a method for the diagnosis or prognosis of metastasis in prostate cancer, as well as a method for determining a propensity for bone metastasis relative to metastasis in other organs, comprising: It also relates to a method comprising the step of determining the MAF expression level. Finally, the present invention relates to the use of c-MAF inhibitors as therapeutic targets for treating prostate cancer. |