http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016500101-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072 |
| filingDate | 2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2016500101-A |
| titleOfInvention | Cytotoxic 2 ', 5'-dideoxy-5-fluorouridine derivatives, process for their production and use thereof |
| abstract | The subject of the present invention is a novel 2 ′, 5′-dideoxy-5-fluorouridine derivative of the general formula 1 Wherein R 1 represents a fragment of a quina alkaloid having an absolute configuration defined at the C8 and C9 atoms. In a second aspect, the subject of the present invention is a process for the preparation of 2 ′, 5′-dideoxy-5-fluorouridine derivatives of general formula 1. In a third aspect, the subject of the invention is the use of a 2 ′, 5′-dideoxy-5-fluorouridine derivative of general formula 1 according to the invention in the anticancer treatment of breast cancer, cervical cancer, lung cancer and nasopharyngeal cancer It is. [Selection figure] None |
| priorityDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.