| abstract |
Disclosed are compositions and methods for treating a sigma-2 receptor mediated disease or disorder comprising treating one or more symptoms of a sigma-2 receptor mediated disease or disorder. . A pharmaceutical composition for treating or alleviating at least one negative symptom of schizophrenia in a subject, comprising a compound represented by formula (II), or a pharmaceutically acceptable salt thereof, water Japanese solvate or solvate. A pharmaceutical composition used for administration to a subject in need of such treatment or alleviation at a dose of 1 to 64 mg per day. [Selection figure] None |