abstract |
PROBLEM TO BE SOLVED: To provide an Fc binding protein having improved stability of Fc binding protein, particularly stability against heat and acid, a method for producing the protein, and an antibody adsorbent using the protein. An Fc-binding protein having improved stability to heat and acid by substituting an amino acid residue at a specific position in an extracellular region with another specific amino acid in human FcγRIIIa, The said subject is solved by the manufacturing method and the antibody adsorption agent using the said protein. [Selection] Figure 5 |