| abstract |
Immunologically active recombinant binding proteins (especially single chain fusion proteins specific for TCR complexes or components thereof), and autoimmune diseases and other disorders or situations (eg, grafts) Compositions and methods for treating rejection) are provided. The present invention relates to fusion proteins that bind to a TCR complex or a component thereof, compositions and unit dosage forms comprising such fusion proteins, polynucleotides and expression vectors encoding such fusion proteins, solids Methods are provided for reducing organ transplant rejection or for treating autoimmune diseases, as well as methods for detecting T cell activation. [Selection figure] None |