| abstract |
PROBLEM TO BE SOLVED: To provide a method for delaying progression or treatment of a proliferative disease, preferably multiple myeloma. (A) N-hydroxy-3- in the preparation of a drug comprising (a) an HDAC inhibitor and (b) an anti-thrombocytopenic agent for use as a multiple myeloma drug. [4-[[[2- (2-Methyl-1H-indol-3-yl) -ethyl] -amino] methyl] phenyl] -2E-2-propenamide or a pharmaceutically acceptable salt thereof (b ) Use in combination with antithrombocytopenic drugs. (B) The combination wherein the antithrombocytopenic is eltrombopag, romiplostim, or both. [Selection figure] None |