| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0249c8c96ed09a989cb0d43c51a3060d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01184 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 |
| filingDate |
2016-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef09d3a61b31a7003778f02bf0a5356
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_826e3121b58539cc48642167df4993c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5846c55c189e2c85c52765783b36f951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9394f75a0ee79e4fe7574b08679c05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22c4259b9ac6c5da180da34eac2225f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8fbb37d4255ca0787e782826c256aef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a77c91ab8867f10470e027de21619d76 |
| publicationDate |
2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2016105739-A |
| titleOfInvention |
A ketoreductase polypeptide for the reduction of acetophenone |
| abstract |
A ketoreductase polypeptide for the reduction of acetophenone is provided. Enzymes belonging to the ketoreductase or carbonyl reductase class (EC 1.1.1.184) are those of optically active alcohols from the corresponding pro-stereoisomeric ketone substrate and by stereospecific reduction of the corresponding racemic aldehyde substrate. Useful for synthesis. The present disclosure provides modified ketoreductase enzymes that have improved properties compared to naturally occurring wild-type ketoreductase enzymes. Also provided are polynucleotides that encode the modified ketoreductase enzyme, host cells capable of expressing the modified ketoreductase enzyme, and methods of synthesizing various chiral compounds using the modified ketoreductase enzyme. [Selection] Figure 1 |
| priorityDate |
2007-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |