abstract |
A Nogo receptor antagonist is provided. Immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptor and fusion proteins, and nucleic acids encoding them are disclosed. Also disclosed are Nogo receptor antagonist polynucleotides. Also disclosed are compositions comprising such Nogo receptor antibodies, antigen binding fragments thereof, soluble Nogo receptors and fusion proteins, nucleic acids encoding them and antagonist polynucleotides, and methods of making and using the same. [Selection figure] None |