| abstract |
Provided are compositions useful for the diagnosis and treatment of tumors in mammals and methods of using these same compositions. An isolated antibody comprising a specific Kabat complementarity determining region (CDR) sequence, a cell producing the antibody, an isolated nucleic acid encoding the antibody, and a mammal using the antibody A method of diagnosing the presence of a tumor in an animal and a method of therapeutically treating a mammal having a cancerous tumor. In addition, any one of the VH acceptor human consensus framework sequences of some specific sequences, and any one of the VL acceptor human consensus framework sequences of some other specific sequences, An isolated antibody comprising. [Selection figure] None |