| abstract |
A minimally invasive controlled drug delivery system and method for use in delivering one or more specific drugs to the eye or the like. Angiogenesis-inhibiting steroids, metalloproteinase inhibitors, VEGF, pigment epithelium-derived factors, urokinase octamer peptide fragments, modified RNA, modified DNA, immunoglobulin derived from the pore Including organic polymers, inorganic polymers, biopolymers, etc., capping pores or surrounding materials with multi-layered silicon having a particle size of 0.1 μm to 100 μm, including drugs and bioactive agents such as dexamethasone A device wherein the inner wall of the pore is shaped by chemical modification with one of the group consisting of functional alkenes, silicon oxides, functional organic halides, and metals to further adjust the release profile of the pores. [Selection figure] None |