| abstract |
The present invention provides identification and enrichment of cell subpopulations. In accordance with the teachings herein, the inventors have used independently or collectively for accurately identifying, sorting, enriching and / or characterizing cancer stem cells from a wide variety of tumor types. Found a series of markers that can The present invention achieves these and other objectives and broadly identifies and characterizes specific tumorigenic cells or subpopulations associated with hyperproliferation or neoplastic disease and, if desired, It is directed to methods, compounds, compositions, and products that can be used to isolate, fractionate, separate or concentrate. In preferred embodiments, the cells or subpopulations of interest comprise tumor initiating cells and / or tumor permanent cells and / or tumor precursor cells. [Selection figure] None |