| abstract |
The present invention relates to a compound for use in a state responsive to cardiovascular disease, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and nitroxyl therapy, a pharmaceutical composition and kit containing the compound, and the compound or pharmaceutical composition. Providing a method to use. A bisacylated hydroxylamine derivative compound represented by formula (1), or a pharmaceutically acceptable salt, hydrate or solvate thereof. (L is a bond, SO 2 or O; Y is alkyl, aryl, heteroaryl or benzyl; R 1 and R 2 are each independently H, alkyl, heterocycloalkyl, aryl, amino, etc.) [Selection figure] None |