| abstract |
The main object of the present invention is to provide a human hepatocyte in which the activity of a cytochrome P450 molecular species is induced, and a method for producing S9 from the cell. A method for inducing a plurality of cytochrome P450 activities by culturing human hepatocytes in a medium containing indirubin, trichostatin A, forskolin and all-trans retinoic acid, and S9 fraction from human cells obtained by the treatment How to make a minute. [Selection] Figure 1 |