abstract |
Disclosed is a compound that activates sphingosine-1-phosphate receptor subtype 1 (S1P1). A novel oxadiazole derivative that selectively activates S1P1 of a receptor as compared to subtype 3 (S1P3) of a sphingosine-1-phosphate receptor. Use and methods for the treatment of abnormal conditions where S1P1 activation, agonism, inhibition or antagonism is medically indicated. [Selection figure] None |