http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016041075-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b65747ed78f05dd9ebe107b50ce2855 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2015-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecf492b38a9327d999119998702b3c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adda1fc77edc2f9ca07351b81bacfc2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dbe5f856a0bb7787f8d7f2d513b2436 |
| publicationDate | 2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2016041075-A |
| titleOfInvention | Modified biotin-binding protein |
| abstract | Avidin or streptavidin and the like have extremely strong binding to biotin, so that the binding cannot be dissociated. Reversible binding is required for the purification of biotinylated biomolecules such as by affinity chromatography. Provision of a modified biotin-binding protein capable of reversible binding. [MEANS FOR SOLVING PROBLEMS] Mutation is introduced into wild-type tamavidin 2 with biotin-binding activity derived from the edible mushroom basidiomycete Tamogitake, by modifying the sequence of specific amino acids, thereby adjusting hydrogen bonding and binding biotin Then, a target modified biotin-binding protein having a biotin-binding ability that can be dissociated and having protease resistance was obtained. [Selection figure] None |
| priorityDate | 2009-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.