| abstract |
An immunogenic composition comprising a polypeptide obtained from Staphylococcus aureus and a polysaccharide. Isolated S. aureus clamping factor A (ClfA) polypeptide, isolated S. aureus clamping factor B (ClfB) polypeptide, isolated S. aureus MntC protein, carrier protein At least three components selected from isolated S. aureus capsular polysaccharide type 5 conjugated to or isolated S. aureus capsular polysaccharide type 8 conjugated to a carrier protein An immunogenic composition. An immunogenic composition wherein the polypeptide is a polypeptide fragment comprising a fibrinogen binding domain of ClfA or ClfB. [Selection figure] None |