http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016032480-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00
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filingDate 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fdac8feb51bffebef4fc368f96b35bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbf5929793bbd73585a1cb1cc48fbbce
publicationDate 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2016032480-A
titleOfInvention Molecular prognostic signature and its use to predict distant metastasis of breast cancer
abstract The present invention provides a molecular prognostic signature and its use for predicting distant metastasis of breast cancer. The present invention is based on a unique 14 gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and analyzing the expression levels of these genes, and methods of using expression level information to predict the risk of breast cancer metastasis. In one aspect of the invention, the genes known as CENPA, PKMYT1, MELK, MYBL2, BUB1, RACGAP1, TK1, UBE2S, DC13, RFC4, PRR11, DIAPH3, ORC6L and CCNB1 in estrogen receptor positive tumor cells of breast cancer patients It relates to a method of measuring the risk associated with tumor metastasis in breast cancer patients, comprising measuring mRNA expression and predicting the risk of tumor metastasis based on the mRNA expression level of these genes. [Selection figure] None
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021205828-A1
priorityDate 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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