| abstract |
The present invention provides a composition that alleviates multiple side effects caused by opioid therapy or opioid receptor activity in a subject undergoing opioid therapy. SOLUTION: Methylnaltrexone represented by the formula (I) or a salt thereof and an excipient such as sodium dodecyl sulfate which optionally forms an ion pair when dissolved in a solution, optionally disintegration of sodium hydrogencarbonate or the like. A pharmaceutical composition for oral administration further comprising an agent. [Selection figure] None |