| abstract |
A fully human monoclonal antibody that specifically binds to GPNMB and uses thereof. Amino acid sequences comprising sequences corresponding to heavy and light chain sequences spanning heavy and light chain immunoglobulin molecules, in particular spanning the framework and / or complementarity determining regions (CDRs) and encoding them A base sequence is provided. The present invention also provides immune complex conjugates comprising anti-GPNMB antibodies and methods of using such immune conjugates. Furthermore, the present invention provides bispecific antibodies comprising an anti-GPNMB antibody component and an anti-CD3 component and methods of using such bispecific antibodies. [Selection] Figure 1 |