abstract |
A method for inducing an immune response against a pathogen of the genus Mycobacterium spp. (I) one or more first immunogenic polypeptides derived from the pathogen; (ii) one or more heterologous encoding one or more second immunogenic polypeptides derived from the pathogen. One or more adenoviral vectors comprising the polynucleotide; and (iii) administering an adjuvant, wherein the one or more first immunogenic polypeptides, the one or more adenoviral vectors and the adjuvant are administered in combination. Methods, and vaccines, pharmaceutical compositions, kits and methods of using the polypeptides, adenoviral vectors and adjuvants. [Selection figure] None |