| abstract |
PROBLEM TO BE SOLVED: To provide a fine particle having an adsorbed polypeptide-containing molecule formed without using a surfactant and a method for producing such a fine particle composition. (Α-hydroxy acid), polyhydroxybutyric acid, polycaprolactone, polyorthoester, polyanhydride, polycyanoacrylate, etc.) are used. A preferred polymer is poly (D, L-lactide-co-glycolide), more preferably having a lactide / glycolide molar ratio in the range of 40:60 to 60:40 and 20,000 daltons to 70, Poly (D, L-lactide-co-glycolide) having a molecular weight in the range of 000 daltons. Preferred polypeptide-containing molecules are bacterial and viral antigens. [Selection figure] None |