Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f86541929ceef0fae0c9c8b7783ccfce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbd211e8dd496ddf7abf25a01d301cb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-385 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6879 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2015-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d6f7837720a2c207ece2792e824463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5520c3548c37673e44b55b481db35fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46cdfa67a151554e73ebd6ca5da822a1 |
publicationDate |
2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2016000057-A |
titleOfInvention |
Processes and compositions for enrichment based on methylation of fetal nucleic acids from maternal samples useful for non-invasive prenatal diagnosis |
abstract |
A process and composition for enrichment based on methylation of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnosis. Compositions and processes are provided that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate, or enrich fetal nucleic acid from a maternal sample. . The compositions and processes described herein are particularly useful for non-invasive prenatal diagnosis, including detecting chromosomal aneuploidy. The present invention specifically includes fetal genetic traits including, but not limited to, fetal chromosomal abnormalities such as the presence or absence of fetal nucleic acid, absolute or relative amount of fetal nucleic acid, fetal gender, and aneuploidy. The present invention provides human epigenetic biomarkers useful for non-invasive detection. [Selection figure] None |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11040349-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019092494-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6447765-B1 |
priorityDate |
2009-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |