| abstract |
Described herein are anti-MCAM antibodies and antigen-binding fragments thereof that can inhibit the interaction between MCAM and its ligand, the laminin alpha-4 chain-containing protein. These anti-MCAM antibodies and antigen-binding fragments thereof may be effective in treating inflammatory conditions characterized by, for example, infiltration of MCAM-expressing cells into inflamed areas in the body. [Selection] Figure 8A |